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ORIGINAL ARTICLE
Year : 2012  |  Volume : 1  |  Issue : 2  |  Page : 86-89

Device associated nosocomial infections and patterns of antimicrobial resistance at a tertiary care hospital


Department of Microbiology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India

Correspondence Address:
Banda Venkata Ramana
Assistant Professor, Department of Microbiology, Sri Venkateswara Institute of Medical Sciences, Tirupati - 517507, Andhra Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2277-8632.98341

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Aim : This prospective study was carried out over a period of 1 year in a tertiary care teaching hospital. The aim of the study was to determine the organisms causing device-related nosocomial infections and to study their anti-microbial resistance pattern. Materials and Methods : Patients with endotracheal intubation, and central venous catheters (CVC)/venous cut down catheters were included in the study. Colonization of the endotracheal tube and colonization of the CVC/venous cut down catheters was studied. Results: The most common organisms isolated from endotracheal tube tips were Pseudomonas aeruginosa (35%), Klebsiella pneumoniae (18%), Escherichia coli (15%), other enterobacteriaceae (19%), non-fermenting gram-negative bacilli (NFGNB) (13%), and methicillin-resistant Staphylococcus aureus (MRSA) (40%). Pseudomonas aeruginosa was the commonest organism, which showed highest frequency of resistance to gentamicin (81%) and ceftazidime (76%). The common organisms isolated from the vascular catheter tips were pseudomonas (30%), Klebsiella pneumoniae (18%), Escherichia coli (16%), other enterobacteriaceae (25%), NFGNB (11%), and MRSA (65%). Similar to ET tubes, here also pseudomonas aeruginosa was the commonest organism with maximum frequency of resistance to ceftazidime (69%). Conclusion: Knowledge of the resident microbial flora and their anti-microbial susceptibility pattern is necessary for formulating a rational antibiotic policy in a hospital.


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