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REVIEW ARTICLE
Year : 2013  |  Volume : 2  |  Issue : 1  |  Page : 10-14

Lysosomal storage diseases: A review with dental abnormalities


Department of Oral and Maxillofacial Pathology, Sree Balaji Dental College and Hospital, Bharath University, Chennai, India

Correspondence Address:
Sudha Jimson
Department of Oral and Maxillofacial Pathology, Sree Balaji Dental College and Hospital, Bharath University, Chennai
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2277-8632.108505

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Cells are made of many organelles. One of those organelles is lysosome, which are cellular organelles and are the first line of defense. They are found only in animal cells. Their main function is destroying foreign bodies that could harm the cell. They get rid of unwanted matter and also help in repair of damaged plasma membrane and seal the wound. Lysosomal storage diseases (LSD) are metabolic disorders caused by deficiency of a single gene. There are about 50 groups of diseases found which are mostly autosomal inherited and few are X-linked inheritance. No cure for LSDs has been found yet and they are mostly symptomatic. Recently, progress has been made in the treatment of LSDs.


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