Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Print this page Email this page Users Online: 1093
Year : 2016  |  Volume : 5  |  Issue : 4  |  Page : 250-254

A Study of metastasis to brain with emphasis on rare tumors and role of immunohistochemistry

Department of Pathology, Guntur Medical College, Guntur, Andhra Pradesh, India

Correspondence Address:
Rajani Mutyala
Department of Pathology, Guntur Medical College, Guntur, Andhra Pradesh
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2277-8632.196557

Rights and Permissions

Introduction: Secondary involvement of the central nervous system (CNS) by direct extention or hematogenous metastasis is a common complication of systemic cancer. Adenocarcinoma was the most common metastatic deposit in the present study, along with a few rare cases such as metastasis from hepatoblastoma, follicular variant of papillary carcinoma, and germ cell tumor of the testis. Aim: This study was undertaken to know the incidence of secondary deposits in the brain. Age, sex, location in the brain, and type of malignancy were studied. In rare cases, immunohistochemistry was done to assess the exact histopathological confirmation. Material and Methods: This study was carried out on a retrospective basis in our institution from March 2012 to July 2015. During the 3 year period, a total of 33 metastatic tumors were diagnosed based on hematoxylin and eosin stained sections of formalin-fixed and paraffin-embedded biopsy specimens. Results: Out of 33 metastatic deposits, adenocarcinoma was the most common secondary deposit in the CNS. In addition, we encountered metastatic deposit from the follicular variant of papillary carcinoma, germ cell tumor from the testis, and hepatoblastoma. Immunohistochemical study was done in a selective cases. Conclusion: This study highlights rare metastatic deposits in the CNS.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded138    
    Comments [Add]    

Recommend this journal