Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Print this page Email this page Users Online: 107
REVIEW ARTICLE
Year : 2017  |  Volume : 6  |  Issue : 2  |  Page : 73-81

Synergetic immunotherapies and current molecular targets in oral cancer treatment


1 Department of Oral Pathology and Microbiology, Vishnu Dental College, Vishnupur, Andhra Pradesh, India
2 Department of Oral Pathology, SJM Dental College, Chitradurga, Karnataka, India

Correspondence Address:
N Pallavi
Department of Oral Pathology and Microbiology, Vishnu Dental College, Vishnupur, Bhimavaram - 534 202, Andhra Pradesh
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JDRNTRUHS.JDRNTRUHS_6_17

Rights and Permissions

The development of cancer therapies depends on identifying exploitable differences between the host immune response and the tumorigenicity. These include anatomic, metabolic, cell cycle kinetics, and presumed antigenic differences between the normal tissue and tumor cells. Immunotherapy also called biologic therapy is a treatment that uses body's own immune system to fight against cancer. Cells such as dendritic cells (DCs), natural killer cells, effector T-cells, and molecules such as complement can be used in various treatment modalities which are segregated as “active” and “passive” based on their ability to engage the host immune system. Further both active and passive immunotherapies can be subdivided into specific and nonspecific approaches. Thus, it is essential to understand the therapeutic approaches and the vaccines made based on the role played by these cells and molecules to circumvent the barriers of tumor microenvironment for an antitumor response. Hence, through this article efforts were made to comprehensively explain the concepts of cancer vaccines and immunotherapies in the treatment of oral cancer.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed655    
    Printed7    
    Emailed0    
    PDF Downloaded133    
    Comments [Add]    

Recommend this journal