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Year : 2012  |  Volume : 1  |  Issue : 3  |  Page : 152-155

Prevalence of thrombocytopenia in a diagnosed case of malaria in rural population of South India

Department of General Medicine, Bhaskar Medical College Yenkapally, Moinabad, Rangareddy District, Andhra Pradesh, India

Correspondence Address:
Sunkara Srinivas
Bhaskar Medical College, Yenkapally, Moinabad, Rangareddy District, Andhra Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2277-8632.102438

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Introduction: Malaria is a major health problem in the tropics and poses a significant burden on health expenditure. Malaria is a common disease in rural India with high mortality and morbidity. Falciparum malaria is common in rural India and presents with protean manifestations, involving multiple systems and high mortality. Compared to benign malaria, Plasmodium falciparum malaria progresses to life-threatening complications, more so in rural India. The global case-fatality rate of falciparum infection is around 2 million deaths per year. Objective: To evaluate the incidence of thrombocytopenia in malaria, its variations in falciparum and vivax; and prognosis of patients with significant thrombocytopenia. Materials and Methods: Platelet count was done on a fully automated, quantitative, hematology Coulter analyzer (Name: I Count 3, Irish Company, 2010 model) for a sample collected from peripheral smear positive for malaria patient. Results: The mean platelet count in vivax infections wasis 120454.55/ml ranging from of 36,000 to 263,000 and in falciparum infections the mean platelet count was 118,200 with a range of 13,000-667,000. Conclusions: Low platelet counts observed in the course of malaria illness are transient and do not necessarily have prognostic implications or platelet infusions more so with the relatively benign course in Plasmodium vivax malaria.

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