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CASE REPORT
Year : 2015  |  Volume : 4  |  Issue : 3  |  Page : 196-198

Sepsis presenting as acute hemorrhagic leukoencephalopathy: A rare case report


1 Department of Neurology, Sri Aurobindo Medical College and PG Institute, Indore, Madhya Pradesh, India
2 Department of Radiology, Sri Aurobindo Medical College and PG Institute, Indore, Madhya Pradesh, India

Correspondence Address:
Om Prakash Lekhra
Quince 205, Shalimar Township, AB Road, Indore, Madhya Pradesh
India
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Source of Support: Nil., Conflict of Interest: None declared.


DOI: 10.4103/2277-8632.165408

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Sepsis-associated encephalopathy (SAE) refers to a clinical spectrum of acute neurological dysfunction that arises in the context of sepsis. Although the pathophysiology of SAE is incompletely understood, it is thought to involve endothelial activation, blood — brain barrier leakage, inflammatory cell migration, and neuronal loss with neurotransmitter imbalance. SAE is associated with a high risk of mortality. Imaging studies using MRI and CT have demonstrated changes in the brains of patients with SAE that are also seen in disorders such as stroke.


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